A one-year trial of naltrexone vs disulfiram in alcohol treatment
Posted on 2013-07-23 22:26:50
Using evidence-based addiction treatment, individuals can learn a self-empowering approach to overcome addiction.
Naltrexone vs Disulfiram
Naltrexone and disulfiram are both used as deterrent agents in addiction treatment. Naltrexone is an opioid receptor agonist that reduces the euphoria associated with alcohol consumption and thus reduces the risk of relapse in alcohol-dependent individuals. Disulfiram blocks the metabolism of acetaldehyde, an intermediate product of alcohol metabolism. Upon consumption of alcohol, increased acetaldehyde levels cause a disulfiram-ethanol reaction, which includes flushing, nausea, vomiting, and a sense of uneasiness. Researchers in Mumbai, India, compared the efficacy of naltrexone and disulfiram in alcohol treatment for dependence in a one-year tria...
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